Continuous Chromatography
Continuous chromatography enables continuous separation and purification by switching multiple columns. Compared with single-column batch purification, it can reduce the use of affinity media, shorten process time, save equipment space, and lower production cost. YMC offers Contichrom CUBE for laboratory evaluation and Contichrom TWIN for GMP production.
| Purity / Recovery | Buffer / Solvent | Maintenance | Features | |
|---|---|---|---|---|
| Single-column batch purification | Good | Moderate | Excellent | Simple operation and easy principle |
| Multi-column continuous purification | Excellent | Excellent | Moderate | Complex system configuration |
| Twin-column continuous purification | Excellent | Excellent | Excellent | Flexible process with easy method setup |
YMC twin-column chromatography supports cost reduction and shorter purification time for antibodies, proteins, peptides, oligonucleotides, low molecular compounds, and impurities.
Recycles low-purity fractions with fresh sample to achieve high purity and recovery.
Maximizes utilization of affinity media and improves productivity.
Combines two chromatography modes with two connected columns.
Concentrates and isolates trace target components efficiently.
